Bioss Inc.'s LC3A Monoclonal Antibody, ALEXA FLUOR® 555 Conjugated is a Mouse monoclonal antibody. The LC3A Monoclonal Antibody, ALEXA FLUOR® 555 Conjugated was generated using MAP1LC3A as the antigen. It reacts with Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Immunocytochemistry, and Immunofluorescence.
Description
Microtubule-associated MAPILC3A constitutes nearly half of the mass of all the microtubule associated proteins that copurify with brain microtubules. MAP1LC3A is one of three human orthologs of the rat Map1LC3, (named MAP1LC3A, MAP1LC3B, and MAP1LC3C). The three isoforms of human MAP1LC3 exhibit distinct expression patterns in different human tissues and also differ in their post-translation modifications. MAP1LC3A and MAP1LC3C are produced by the proteolytic cleavage after the conserved C-terminal Gly residue; MAP1LC3B does not undergo C-terminal cleavage and exists in a single modified form